I always carry TP and with me, you never know when it will come in handy
I grab a business card from where I am staying. That way when I get lost I can just show the card to a cab driver or ask a local for help.
Walk into every adventure with an open mind...
Driving though Southern Patagonia? Take the Chilean side - the carretera austral, otherwise it's days and days of endless, unpaved highways through the pampas.
In Peru, skip the cuy and try the alpaca!
When u visit Istanbul Turkey do not go outside with wet hair EVER (they might think ur a prostitute), don't look men in the eyes (it constitutes extreme flirting), and bring flowers to someones house if ur a guest:)
you live once, plan it now or you'll never do it.
Bring a good pair of ear plugs so you can sleep on the plane and be ready to go when you get to your destination.
always have a positive outlook, but don't always be too confident about it.
When I visit... I try to experience all aspects of the local culture. I approach travel like I would a class; I'm in a new place to learn.